Auteurs:
Prof. Dr. Ines Mürner-Lavanchy | Faculty of Psychology, University of Basel | Switzerland
Dr. Stefan Lerch
Christian Hertel
Dr. Selina Schär
Prof. Dr. Julian Koenig
Prof. Dr. med. Michael Kaess
Introduction: There is increasing evidence on the transdiagnostic symptom of irritability as a predictor of suicidal thoughts and behaviors. However, little is known on irritability as a proximal indicator, occurring immediately before adolescents engage in suicidal behaviors. Ecological momentary assessment (EMA) has the potential to examine temporal changes of affective states, in a non-laboratory setting and unbiased by retrospective recall. Thereby, it might in the future improve short-term prediction of suicidal behavior. The present study seeks to investigate whether momentary irritability is associated with suicidal thoughts and self-harm in adolescent in-patients.
Method: Intensive EMA on irritability and suicidal thoughts as well as self-injury were collected from n = 49 adolescent in-patients. Patients were prompted hourly, twelve times a day for five consecutive weekdays. Logistic multilevel and mixed linear regression were used to examine associations between momentary irritability and suicidal thoughts, the intensity of suicidal thoughts, self-harm as well as the urge to self-harm. Lagged models examined whether irritability from one sampling was able to predict suicidal thoughts and behaviors in the next sampling.
Results: In total, n = 2066 EMA samplings were obtained, with an average of 4.3 (SD = 1.1) days of participation and 42.2 (SD = 17.6, range 3 - 60) prompts answered. Overall, higher irritability was associated with higher odds for self-harm (OR = 1.02 [95%CI = 1.00, 1.03], p < .001; urge to self-harm: b = 0.18 [0.15, 0.21], p < .001) and suicidal thoughts (OR = 1.03 [95%CI = .03, 1.04], p < .001; intensity of suicidal thoughts: b = 0.17 [0.14, 0.21], p < .001). Higher irritability further predicted the presence of suicidal thoughts at the next sampling, i.e. one hour later (OR = 1.02 [1.01, 1.02], p < .001), as well as two, three and four hours, but not five hours later (OR = 1.0 [0.99, 1.01], p = .48). Similarly, higher irritability predicted self-harm one and two, but not three hours later.
Conclusion: Self-reported states of momentary irritability were associated with the presence and intensity of suicidal thoughts and self-harm. However, across models, effect sizes were small. While self-reported momentary irritability may have some potential as a proximal indicator of suicidal thoughts and self-harm in adolescent patients, this research needs replication and will benefit from further refinement of irritability EMA.