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Contribution title Clinical Significance of Psychotic Experiences in Preadolescent Children with Non-Psychotic Mental Disorders - The Danish High Risk and Resilience Study, VIA 11
Contribution code D3.154
Authors
  1. Maja Gregersen Child and Adolescent Mental Health Center, Capital Region, Copenhagen, Denmark Presenter
  2. Sinnika Birkehøj Rohd CORE- Copenhagen Research Center for Mental Health
  3. Anne Søndergaard Copenhagen Research Center for Mental Health - CORE
  4. Julie Marie Brandt Copenhagen Research Center for Mental Health, Mental Health Services in the Capital Region of Denmark
  5. Jens Richardt Møllegaard Jepsen Mental Health Center, Capital Region, Copenhagen, Denmark
  6. Lotte Veddum The Psychosis Research Unit, Aarhus University Hospital, Denmark
  7. Christina Bruun Knudsen Aarhus University Hospital Psychiatry
  8. Anna Krogh Andreassen The Psychosis Research Unit, Aarhus University Hospital Psychiatry, Denmark
  9. Carsten Hjorthøj Copenhagen Research Center For Mental Health - Core
  10. Mette Falkenberg-Krantz Child and Adolescent Mental Health Center, Mental Health Services – Capital Region of Denmark
  11. Aja Neergaard Greve Aarhus University Hospital Psychiatry
  12. Ole Mors The Psychosis Research Unit, Aarhus University Hospital, Denmark
  13. Merete Nordentoft Psykiatrisk Center København
  14. Nicoline Hemager Copenhagen Research Center for Mental Health, Mental Health Services in the Capital Region of Denmark
  15. Anne Amalie Elgaard Thorup Mental Health Center, Capital Region
Form of presentation Poster
Topic
  • T45 - Birth Cohorts and longitudinal studies
Abstract Aims: We aim to examine whether presence of psychotic experiences, i.e. subclinical hallucinations and delusions, is associated with higher severity of other psychopathology in children with non-psychotic Axis I mental disorders during middle childhood.

Methods: Children (n = 157, mean age 12.0) at familial high-risk of schizophrenia (n = 78) or bipolar disorder (n = 40) and population-based controls (n = 39) were assessed for psychotic experiences, dimensional psychopathology, comorbidity, global functioning, and impact of psychopathology on everyday life, during middle childhood.

Results and Conclusions: Presence of psychotic experiences was associated with higher
scores on internalizing (Cohen’s d 0.42, p = .02) and total dimensional symptoms (Cohen’s d 0.40, p = .02) and higher rates of comorbid mental disorders (OR 2.2, p = .04) after accounting for familial risk. Furthermore, children with psychotic experiences were more likely to report impact of psychopathology on everyday life after accounting for number of concurrent mental disorders and familial risk (OR 2.5, p = .01). In preadolescent children with non-psychotic mental disorders, psychotic experiences mark higher severity of concurrent non-psychotic psychopathology. Psychotic experiences should be routinely assessed in child and adolescent mental health services.