Experiences of maltreatment display a burden to children and adolescents worldwide with prevalence rates of as high as 14-55% for physical abuse, 11-47% for emotional abuse, and 6-22% for sexual abuse. Children and adolescents vary in the nature of their responses to trauma and maltreatment. The reactions of individual youths may be influenced by their developmental level, ethnicity/cultural factors, previous trauma exposure, available resources, and preexisting child and family problems. However, the exposure to abuse and neglect was found associated with a host of negative outcomes in later adolescence and adulthood, such as suicide, depression, alcohol use, drug use, and physical consequences, such as autoimmune disorders. Furthermore, some seriously maltreated children and adolescents were found at risk for committing criminal offenses. Effective interventions are needed in order to prevent these negative outcomes. This symposium addresses the relation of different trauma types and possible negative outcomes in at risk populations (e.g. juvenile offenders) and illustrates how effective interventions can be implemented into clinical practice.