The last decade has taught us that the most effective method for minimizing the impact of autism spectrum disorders symptoms was early intensive behavioral intervention. While many different approaches have been proposed, it seems that the first three years of life may represent a “window of opportunity”, to get the most optimal long-term benefits. The intensity of intervention is also critical, with some programs offering up to 20h of individual therapy per week. In this symposium, we will share the experience of 5 university centers in Switzerland who started to implement early intervention programs for preschoolers with autism a few years ago. Each center choose the approach which tailored to their needs, trained their team and was able to enroll in average 20 preschoolers with ASD to date. These data are in turn presented regularly to the Swiss invalidity insurance in an effort to demonstrate that local programs can dramatically help improving the lives of affected children. After the individual presentations by 4 of these 5 centers, the last talk will present statistical results based on the more than 100 toddlers with ASD who participated in one of these early intervention programs.