Detailed contribution information
| Contribution title | 2280 - AN ASSESSMENT OF THE RELATIONSHIP BETWEEN LYME DISEASE AND AUTISM SPECTRUM DISORDERS |
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| Contribution code | PS02-42 (P) |
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| Form of presentation | Poster |
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| Abstract |
Objective: The aim of this study is the investigation of the relationship between ASD and Lyme disease, which is claimed to possibly have a role in the etiology of ASD. This study has compared whether serologically and clinically there is Lyme disease in 40 children aged between 3-18 years, diagnosed with ASD and their mothers and the 18 siblings of the children with ASD who were taken as the healthy control group. Methods: The Borrelia Burgdorferi antibody was checked in the serums of all participants with ELISA and the WB test was done on all serums in which positivity or border levels were detected. Autism severity was assessed by Childhood Autism Rating Scale (CARS). Denver Developmental Screening Test-II (DDST-II) was used to determine the developmental levels of the children. Results: The results of 4 patients and 1 healthy control whose antibody levels were measured with the WB IgM test were all negative. In 1 of 2 patients (50.0%) who underwent the WB IgG test the result was found negative, and in 1 (50.0%) it was found at the border. In 1 (2.5%) mother who underwent the WB IgM test the result was found as negative, in 2 (33.3%) of 6 mothers who underwent the WB IgG test the result was at the border, and in 4 (66.6%) the result was found as negative. No statistically significant difference was found between the results of the WB test that was performed on the patient and control groups (p>0.05). Conclusions: ASD patients, their mothers and their siblings as healthy controls were evaluated in our study and Lyme disease was not detected serologically or clinically in any of the participants. Keywords: Adolescent, autism spectrum disorders, children, infection, Lyme disease |