Detailed contribution information
| Contribution title | 2388 - Medical comorbidities in children and adolescents with Autism Spectrum Disorders and Attention Deficit Hyperactivity Disorders: a systematic review |
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| Contribution code | PS01-20 (P) |
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| Form of presentation | Poster |
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| Abstract |
Objective: Medical disorders occur more often in adult psychiatric patients than in the general adult population. However, in child and adolescent psychiatry this relation/association is unclear, mainly due to a lack of integration of existing data. To address this issue, we here present a systematic review on the medical comorbidity in two major developmental disorders: autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) and formulate clinical recommendations. Method: The literature was searched with the PubMed and PsycINFO database (2000 –1 June 2016) using the keywords " (((child and adolescent) AND (Autism OR Attention Deficit Hyperactivity Disorder* OR ADHD)) AND ("Cardiovascular Diseases"[Mesh] OR "Endocrine System Diseases"[Mesh] OR "Immune System Diseases"[Mesh] OR "Neurobehavioral Manifestations"[Mesh] OR Somatic OR Autoimmune disease OR Nervous system disease OR Infection OR Infectious disease)).” Two raters independently assessed the quality of the eligible studies. An additional rater was consulted to resolve any scoring differences between raters. Results: The initial search identified 5218 articles. Based on inclusion and exclusion criteria we selected in total 94 papers as relevant considering the topic. Trial quality was assessed according to a standardized and validated set of criteria and yielded 27 studies for inclusion. Conclusion: This thorough literature search provides an overview of relevant articles on medical comorbidity in children with ADHD and/ or ASD. Future studies should focus on broader evaluation of medical disorders to improve treatment algorithm in this vulnerable group. |