Detailed contribution information
| Contribution title | 3340 - Trichotillomania Associated With Aripiprazole: A Case Report |
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| Contribution code | PS01-34 (P) |
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| Form of presentation | Poster |
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| Abstract |
Objective: Aripiprazole is a novel atypical antipsychotic agent which blocks D2 and D3 receptors in hyperdopaminergic states. Besides its antagonist effect, it is the first dopamine D2/D3 receptor partial agonist approved for use in the treatment of psychiatric disorders. However, its partial agonistic effect may cause hyperactivity in the dopaminergic pathway. In literature, this adverse effect was linked to atypical antipsychotic induced obsessive-compulsive symptoms (OCS). With this case report, we aimed to present a male adolescent patient, diagnosed with trichotillomania under aripiprazole treatment. Method: The patient was a 16 year-old-boy with a history of Attention Deficit-Hyperactivity Disorder symptoms and Conduct Disorder symptoms. For the diagnoses, Diagnostic and Statistical Manual of Mental Disorders criteria (DSM-5) was employed. His course of illness, diagnostic procedure and treatment history are described. Results: Aripiprazole treatment was started at 2.5 mg/day for a week, and then the dose was increased to 5 mg/day. At the follow-up appointment, he reported that he had a week long symptom of hair loss on his right vertex scalp after using aripiprazole. The patient described his uncontrollable urge before pulling his hair and the sense of relief afterward. His symptoms stopped 2 days after cessation of aripiprazole treatment. Conclusion: Aripiprazole has lower adverse effects compared to other antipsychotic agents. We report the case of a patient who experienced hair pulling under treatment. This side effects not been reported to date. Trichotillomania is one of the consequences whose effects on social life may prove serious. Clinicians and patients should be aware of the possibility of this adverse effect of aripiprazole. |