Detailed contribution information
| Contribution title | 3463 - Adolescents at Ultra-High-Risk for psychosis: which cognitive particularities? |
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| Contribution code | PS02-27 (P) |
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| Form of presentation | Poster |
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| Abstract |
Background : Schizophrenia is a mental disorder, commonly preceded by a prodromal phase associating a cognitive and functional decline with non-specific and various psychiatric symptoms. This study aimed to point out the cognitive profile in individuals with an Ultra-High-Risk for psychosis (UHR(+)), in order to enrich the screening strategies for this group and thus improve their prognosis. Methods : We carried out a cross-sectional descriptive study involving 33 adolescents referred to the child and adolescent psychiatry department in Razi Hospital between February 2015 and July 2016. UHR(+) and UHR(-) group were defined according to the CAARMS criteria. The cognitive profile was compared between groups. We assessed intelligence, visual memory, verbal memory, attention, executive functions and verbal fluency. Results : Our sample included 33 adolescents aged between 14 and 18. Sex-ratio was 0.57. The majority lived in urban areas and was provided with formal education. School decline was observed in 27 adolescents. Basic health centers, child protection delegates and neurologists referred the majority of our patients. The most common chief complaints were: depressive and/or anxiety symptoms, behavioural disturbances, school decline and suicidal attempts. The most commonly diagnosed disorders included: conduct disorder (24.2%) and adjustment disorder with depressive mood (21.2%). Seventeen participants were UHR (+) while 16 were UHR(-). The UHR (+) group exhibited worse performance in visual memory (p=0.010), executive functions (p=0.024) and verbal fluency (p=0.04). Conclusion : Our results are in accordance with the data of the literature. This suggests that alterations in specific cognitive domains may be specific markers of the UHR(+) individuals. We suggest to provide these individuals with psychoeducation and cognitive remediation. |